Volume No 41 January - June 2021

Pages 1-14:  M Ducret, A Costantini, S Gobert, J-C Farges, M Bekhouche
Fibrin-based scaffolds for dental pulp regeneration: from biology to nanotherapeutics
Dental Regenerative Biology special issue manuscript

Pages 15-30:  R Björkenheim, E Jämsen, E Eriksson, P Uppstu, L Aalto-Setälä, L Hupa, KK Eklund, M Ainola, NC Lindfors, J Pajarinen
Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro

Pages 31-39:  N Kaibuchi, T Iwata, T Okamoto, Y Kawase-Koga, M Yamato
Cell therapy for medication-related osteonecrosis of the jaw: update on treatment strategies
Dental Regenerative Biology special issue manuscript

Pages 40-51: ML Sennett, JM Friedman, BS Ashley, BD Stoeckl, JM Patel, M Alini, M Cucchiarini, D Eglin, H Madry, A Mata, C Semino, MJ Stoddart, B Johnstone, FT Moutos, BT Estes, F Guilak, RL Mauck, GR Dodge
Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model

Pages 52-72: J Melrose, S Tessier, MV Risbud
Genetic murine models of spinal development and degeneration provide valuable insights into intervertebral disc pathobiology
Disc Biology special issue manuscript

Pages 73-89: AJ Hayes, J Melrose
3D distribution of perlecan within intervertebral disc chondrons suggests novel regulatory roles for this multifunctional modular heparan sulphate proteoglycan
Disc Biology special issue manuscript

Pages 90-107: S Tang, A Salazar-Puerta, J Richards, S Khan, JA Hoyland, D Gallego-Perez, B Walter, N Higuita-Castro, D Purmessur
Non-viral reprogramming of human nucleus pulposus cells with FOXF1 via extracellular vesicle delivery: an in vitro and in vivo study
Disc Biology special issue manuscript

Pages 108-120:  M Gallorini, R Di Carlo, S Pilato, A Ricci, H Schweikl, A Cataldi, A Fontana, S Zara
Liposomes embedded with differentiating factors as a new strategy for enhancing DPSC osteogenic commitment
Dental Regenerative Biology special issue manuscript

Pages 121-141: JW Snuggs, RAD Bunning, CL Le Maitre
Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4
Disc Biology special issue manuscript

Pages 142-152:  F Zhang, X Liu, B Li, Z Li, S Grad, D Chen, M Gao, S Liu
The effect of hyaluronic acid on nucleus pulposus extracellular matrix production through hypoxia-inducible factor-1α transcriptional activation of CD44 under hypoxia
Disc Biology special issue manuscript

Pages 153-169:  J Gansau, CT Buckley
Priming as a strategy to overcome detrimental pH effects on cells for intervertebral disc regeneration
Disc Biology special issue manuscript

Pages 170-183: EB Hunziker, Y Liu, M Muff, T Haegi, N Shintani, K Lippuner
The slow release of BMP-7 at a low dose accelerates dental implant healing in an osteopenic environment
Dental Regenerative Biology special issue manuscript

Pages 184-193: SH Zaky, M Shehabeldin, H Ray, C Sfeir
The role of inflammation modulation in dental pulp regeneration
Dental Regenerative Biology special issue manuscript

Pages 194-203: MKM Kim, R Ramachandran, CA Séguin
Spatiotemporal and functional characterisation of transient receptor potential vanilloid 4 (TRPV4) in the murine intervertebral disc
Disc Biology special issue manuscript

Pages 204-215: I Gendviliene, E Simoliunas, M Alksne, S Dibart, E Jasiuniene, V Cicenas, R Jacobs, V Bukelskiene, V Rutkunas
Effect of extracellular matrix and dental pulp stem cells on bone regeneration with 3D printed PLA/HA composite scaffolds
Bone Healing special issue manuscript

Pages 216-232: TT Madanagopal, YK Tai, SH Lim, CHH Fong, T Cao, V Rosa, A Franco-Obregón
Pulsed electromagnetic fields synergize with graphene to enhance dental pulp stem cell-derived neurogenesis by selectively targeting TRPC1 channels
Dental Regenerative Biology special issue manuscript

Pages 233-244: A Ivica, M Zehnder, FE Weber
Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in regenerative endodontics
Dental Regenerative Biology special issue manuscript

Pages 245-268: TK Brenner, K Posa-Markaryan, D Hercher, S Sperger, P Heimel, C Keibl, S Nürnberger, J Grillari, H Redl, A Hacobian
Evaluation of BMP2/miRNA co-expression systems for potent therapeutic efficacy in bone-tissue regeneration

Pages 269-315: J Vun, M Panteli, E Jones, PV Giannoudis
The in vitro effects of platelet products on the biophysiological functions of human bone marrow mesenchymal stromal cells: a systematic review

Pages 316-331: G Cecoro, M Paoletta, M Annunziata, L Laino, L Nastri, F Gimigliano, S Liguori, G Toro, A Moretti, L Guida, G Iolascon
The role of bone anabolic drugs in the management of periodontitis: a scoping review
Dental Regenerative Biology special issue manuscript

Pages 332-344: MT Bergamo, Z Zhang, TM Oliveira, JE Nör
VEGFR1 primes a unique cohort of dental pulp stem cells for vasculogenic differentiation
Dental Regenerative Biology special issue manuscript

Pages 345-354: T-Y Liu, M Bartnikowski, AC Wu, M Veitch, KA Sokolowski, SM Millard, AR Pettit, V Glatt, CH Evans, JW Wells
Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1
Bone Healing special issue manuscript

Pages 355-369: DG Bisson, M Mannarino, R Racine, L Haglund
For whom the disc tolls: intervertebral disc degeneration, back pain and toll-like receptors
Disc Biology special issue manuscript

Pages 370-387:  B Ashinsky, HE Smith, RL Mauck, SE Gullbrand
Intervertebral disc degeneration and regeneration: a motion segment perspective
Disc Biology special issue manuscript

Pages 388-400: C Liebsch, HJ Wilke
The effect of multiplanar loading on the intradiscal pressure of the whole human spine: systematic review and meta-analysis

Pages 401-420:  K Joyce, IL Mohd Isa, A Krouwels, L Creemers, A Devitt, A Pandit
The role of altered glycosylation in human nucleus pulposus cells in inflammation and degeneration
Disc Biology special issue manuscript

Pages 421-430: Y Yuan, Y Ren, M Dijk, GI Geertsema-Doornbusch, J Atema-Smit, HJ Busscher, HC van der Mei
Phagocytosis and macrophage polarization on bacterially contaminated dental implant materials and effects on tissue integration
Dental Regenerative Biology special issue manuscript

Pages 431-453:  JR Ferreira, GQ Teixeira, E Neto, C Ribeiro-Machado, AM Silva, J Caldeira, C Leite Pereira, S Bidarra, AF Maia, M Lamghari, MA Barbosa, RM Gonçalves
IL-1β-pre-conditioned mesenchymal stem/stromal cells’ secretome modulates the inflammatory response and aggrecan deposition in intervertebral disc
Disc Biology special issue manuscript

Pages 454-470: A Wallimann, W Magrath, K Thompson, T. Moriarty, RG Richards, CA Akdis, L O'Mahony, CJ Hernandez
Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing
Bone Healing special issue manuscript

Pages 471-484: A Adoungotchodo, LM Epure, F Mwale, S Lerouge
Citosan-based hydrogels supplemented with gelatine and Link N enhance extracellular matrix deposition by encapsulated cells in a degenerative intervertebral disc environment

Pages 485-501: M EzEldeen, J Loos, Z Mousavi Nejad, M Cristaldi, D Murgia, A Braem, R Jacobs
3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering
Dental Regenerative Biology special issue manuscript

Pages 502-516: P Pagella, A Cordiale, GD Marconi, O Trubiani, M Rasponi, TA Mitsiadis
Bioengineered tooth emulation systems for regenerative and pharmacological purposes
Dental Regenerative Biology special issue manuscript

Pages 517-530:  MP Grant, CR VanderSchee, H Chou, A Bolt, LM Epure, D Kuter, J Antoniou, S Bohle, KK Mann, F Mwale
Tungsten accumulates in the intervertebral disc and vertebrae stimulating disc degeneration and upregulating markers of inflammation and pain
Disc Biology special issue manuscript

Pages 531-545: N Khatib, C Parisi, NC Nowlan
Differential effect of frequency and duration of mechanical loading on fetal chick cartilage and bone development

Pages 546-557: HM Zlotnick, RC Locke, BD Stoeckl, JM Patel, S Gupta, KD Browne, J Koh, JL Carey, RL Mauck
Marked differences in local bone remodelling in response to different marrow stimulation techniques in a large animal
Bone Healing special issue manuscript

Pages 558-575: A Levillain, S Ahmed, D-M Kaimaki, S Schuler, S Barros, D Labonte, JC Iatridis, NC Nowlan
Prenatal muscle forces are necessary for vertebral segmentation and disc structure, but not for notochord involution in mice
Disc Biology special issue manuscript

Pages 576-591: TD Jacobsen, PA Hernandez, NO Chahine
Inhibition of toll-like receptor 4 protects against inflammation-induced mechanobiological alterations to intervertebral disc cells
Disc Biology special issue manuscript

Pages 592-602: MM Menger, B Merscher, C Scheuer, BJ Braun, SC Herath, MF Rollmann, D Stenger, T Später, T Pohlemann, MD Menger, T Histing
Amlodipine accelerates bone healing in a stable closed femoral fracture model in mice
Bone Healing special issue manuscript

Pages 603-615: A-N Zeller, M Selle, Z Gong, M Winkelmann, C Krettek, K Bundkirchen, C Neunaber, S Noack
Osteoporosis is accompanied by reduced CD274 expression in human bone marrow-derived mesenchymal stem cells
Bone Healing special issue manuscript

Pages 616-632: G Monaco, AJ El Haj, M Alini, MJ Stoddart
Sodium hyaluronate supplemented culture medium combined with joint-simulating mechanical loading improves chondrogenic differentiation of human mesenchymal stem cells

Pages 633-647: S Tepic, S Bresina
A biography of the point contact fixator (PC-Fix)
Bone Healing special issue manuscript

Pages 648-667: I Heggli, S Epprecht, A Juengel, R Schuepbach, N Farshad-Amacker, C German, T Mengis, N Herger, L Straumann, S Baumgartner, M Betz, JM Spirig, F Wanivenhaus, N Ulrich, D Bellut, F Brunner, M Farshad, O Distler, S Dudli
Pro-fibrotic phenotype of bone marrow stromal cells in Modic type 1 changes
Disc Biology special issue manuscript

Pages 668-679: V Glatt, CH Evans, K Tetsworth
Reverse dynamisation: a modern perspective on Stephan Perren’s strain theory
Bone Healing special issue manuscript

Pages 680-693: RJ Kim, SH An, JY Gwark, HB Park
Antioxidant effects on hypoxia-induced oxidative stress and apoptosis in rat rotator cuff fibroblasts

Pages 694-706: MG Kontakis, A Diez-Escudero, H Hariri, B Andersson, JD Järhult, NP Hailer
Antimicrobial and osteoconductive properties of two different types of titanium silver coating

Pages 707-738: J Guerrero, S Häckel, AS Croft, S Hoppe, CE Albers, B Gantenbein
The nucleus pulposus microenvironment in the intervertebral disc: the fountain of youth?
Disc Biology special issue manuscript

Pages 739-755: M-A Burch, A Keshishian, C Wittmann, D Nehrbass, U Styger, G Muthukrishnan, D Arens, VA Stadelmann, RG Richards, TF Moriarty, K Thompson
The non-steroidal anti-inflammatory drug carprofen negatively impacts new bone formation and antibiotic efficacy in a rat model of orthopaedic-device-related infection
Orthopaedic Infection special issue manuscript

Pages 756-773: LA van Dijk, F de Groot, H Yuan, C Campion, A Patel, K Poelstra, JD de Bruijn
From benchtop to clinic: a translational analysis of the immune response to submicron topography and its relevance to bone healing
Bone Healing special issue manuscript

Pages 774-792: MI Hofstee, M Riool, F Gieling, V Stenger, C Constant, D Nehrbass, S Zeiter, RG Richards, SAJ Zaat, TF Moriarty
A murine Staphylococcus aureus fracture-related infection model characterised by fracture non-union, staphylococcal abscess communities and myeloid-derived suppressor cells
Orthopaedic Infection special issue manuscript

Pages 793-810: J Speer, M Barcellona, L Jing, B Liu, M Lu, M Kelly, J Buchowski, L Zebala, S Luhmann, M Gupta, L Setton
Integrin-mediated interactions with a laminin-presenting substrate modulate biosynthesis and phenotypic expression for cells of the human nucleus pulposus

Pages 811-833: M Matoug-Elwerfelli, H Nazzal, M Duggal, R El-Gendy
What the future holds for regenerative endodontics: novel antimicrobials and regenerative strategies
Dental Regenerative Biology special issue manuscript